Review of Apoptosis

Submit Manuscript | http://medcraveonline.com Apoptosis was first defined in 1972 [3], as physiological death pattern unlike necrosis. In Ancient Greek, apoptosis means falling of leaves from trees and petals from flowers. Apoptosis is an active procedure that is activated by various traumatic extra cellular lesions (hormonally active various agents, ionized radiation and traumatic agents including chemotherapy) or by genetic factors and that controls cellular death via a mechanism programmed by the cell itself [4]. As a physiological process, apoptosis is the most common morphology occuring in conditions in which cellular death is considered as physiological [5]. Apoptotic cells are continuously formed in some cells and tissues of organism and this process continues throughout all life. Thus death (apoptosis) and reformation (mitosis) proceeds in a dynamic balance by producing hemostasis in these tissues [6].